Vlad Kholodovych

Resume

TRAINING AND EDUCATION

2011 - present Scientific Stuff (Rutgers: IS&T, HPC - RWJMS),
Newark, NJ
2002 - 2011 Post-Doctoral Research Associate (RWJMS-UMDNJ),
Piscataway, NJ
2001 Post-Doctoral Research Associate, Department of Chemistry, University of Missouri St.Louis (UMSL), St.Louis, Missouri, USA
1998 Ph.D., Bioorganic Chemistry, Chemistry of Physiologically Active Compounds, Institute of Bioorganic & Petrochemistry, Ukrainian National Academy of Sciences, Kiev, Ukraine Thesis: “Computational modeling, synthesis and biological tests of peptide immunomodulators”
1993 M.S. in Chemistry, Department of Chemistry of Natural Compounds, Kiev State University, Kiev, Ukraine

 

RECENT AND CURRENT SCIENTIFIC PROJECTS
  • Development of a new computational tools for a rational drug design and QSAR (shape signatures, neural networks and pattern recognition technique)
  • Rational design for biomaterials and biodegradable polymers (QSAR, molecular dynamics, de novo design)
  • Pregnane X receptor (PXR): modeling and design of species-specific ligands (homology modeling, molecular dynamics, pharmacophore search, high-throughput screening, docking, QSAR)
  • Cannabinoid receptor inhibitors: elucidation of the mechanism of action (QSAR CoMFA/COMSIA, pharmacophore modeling, conformational search)
  • Alzheimer's and Parkinson's diseases: modeling of amyloid fibril formation and its spatial organization (molecular dynamics)
  • Na, K-ATPase modeling, and the design of novel inhibitors - congestive heart failure (homology and pharmacophore modeling, conformational search, de novo drug design, docking, 3-D database search)

TEACHING EXPERIENCE

2002-present Lecturer/Instructor, Structural Bioinformatics I, Structural Bioinformatics II and Fundamentals of Bioinformatics Informatics Institute, UMDNJ, Piscataway/Newark, NJ

HONORS

2003 Research Achievement Award, UMDNJ, NJ
2002 Research Achievement Award, UMDNJ, NJ
2002-2003 Young Investigator Award, UMDNJ, NJ
1999-2000  Stipendiary Award of the Ukrainian National Academy of Sci., Ukraine
1998-1999 Stipendiary Award of the Ukrainian National Academy of Sci., Ukraine


MEMBERSHIP
  • American Chemical Society (ACS)
  • New York Academy of Science (NYAS)